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PRT062607 acetate is a research-grade small-molecule inhibitor of spleen tyrosine kinase (Syk), provided as a high-purity solid or as DMSO solutions for laboratory use. It is used in cellular and animal studies to probe Syk-mediated signaling, inflammation, and apoptosis pathways, and is supplied with analytical data to support research applications.
Potent and selective Syk inhibition (IC50 ≈ 1 nM).
High analytical purity (99.83%).
Available as solid powder and 10 mM DMSO solutions for flexibility.
Suitable for in vitro and in vivo preclinical studies.
Supplied with supporting analytical documentation (COA/SDS).
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Icatibant Acetate (CAS No 138614-30-9) is a synthetic peptide and a selective bradykinin B2 receptor antagonist used in biomedical research for its ability to inhibit bradykinin-induced responses Originating from efforts to manage hereditary angioedema it acts by blocking the B2 receptor pathway preventing vasodilation and vascular permeability Its in vitro activity is observed in the nanomolar range It is commonly applied in cell-based assays animal models and drug screening to explore inflammatory responses and vascular permeability Experimental concentrations typically depend on the specific research design
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TL13-112 is a degrader of anaplastic lymphoma kinase (ALK) with an IC50 of 0 60 nM It demonstrates anti-proliferative activity in non-small-cell lung cancer (NSCLC) and anaplastic large cell lymphoma (ALCL) cell lines
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